(412) 586-4678
(412) 586-4678
Low dose naltrexone, where naltrexone is used in doses approximately one-tenth those used for drug/alcohol rehabilitation purposes, is being used as an "off-label" treatment for certain immunologically-related disorders. The use of LDN for such diseases as cancer was first proposed by Ian Zagon, PhD, and LDN's broader clinical effects in humans were proposed by Bernard Bihari, MD. In addition to cancer, LDN is also being used to treat MS as well as Lyme Disease, Thyroid Conditions, Fibromyalgia, Crohn's, SIBO, and Fertility Issues.
LDN has helped me significantly. My pain levels are reduced to nearly nothing. The headaches, which were daily and excruciating, are all gone. Continual nausea is now gone! My energy levels are restored to near normal. My family and friends are excited; my daughters say they have their mom back. My husband is thrilled! All of this after 2 months; however my response to LDN was immediate! LDN helped me to get off Lyrica with no withdrawal symptoms. We are so grateful for a compounding pharmacy in our area with caring staff to prepare this badly needed and effective compounded medication.
I am a 64 year old woman who was 'officially' diagnosed with ms twelve years ago, but who has had symptoms since I was 19 when I had an incidence of numbness. I was diagnosed in my 20's with 'fibromysitis' which was renamed fibromyalgia in my 30's. The two key symptoms were EXTREME fatigue and INTENSE muscle ache, which nothing could remedy. Throughout the last 40 years I have been told that I have irritable bowel, mitral valve prolapse causing chest pain(which was muscular), upper back pain, asthma, dizziness, allergies. You get the picture...a garbage bag of symptoms that flared up then faded away.Yet, when I told the doctors that I was having cognitive difficulties, no one thought that it was due to MS or FIBROGARBAGE. Twelve years ago I had a bout with optic neuritis, and an MRI and spinal tap confirmed MS. I started on AVONEX, but had a bad reaction, so I stopped taking anything for about a year and had another flare up of optic neuritis. I then began to take REBIF, which seemed to control the flares. I was wipe-out tired, not sleepy tired----there is a difference, because no amount of sleep would alleviate the exhaustion and I still had incredible aching muscles, but I appeared ok. My short term memory continued to get worse and while I could process everything I read with no trouble, I could not retain much of it. VERY FOGGY. About 5 years ago, I discovered LDN and started taking it at 4.0 mg.(In this last month I have upped the dosage to 4.5 ) My reasoning was that since I had NO side effects ,why not take the recommended dosage and see IF I notice any change.(I DON"T) Since I also take REBIF(22mcg) three times a week,I have no way of actually knowing which of the drugs has slowed the progression of my symptoms, but I can say that I have not had another bout of optic neuritis. After beginning LDN I was convinced that it had a positive effect on me---even. I am convinced that LDN has had a positive effect on me---I just can't explain how or why. I had a bump in cognitive ability about 6 months ago,when I started to use estriol/progesterone creams, and for a couple of months, I actually felt like my old self. That is not the case today. As of today, I am taking various supplements, using the creams, taking LDN and REBIF and my muscles are getting weaker.EXERCISE has been absent from this description and when I am able to exercise,even minimally, I do feel better. The problem is that I am always too tired to do so. IF I were to meet someone newly diagnosed, I would FIRST begin with LDN, and I would allow that a good amount of time before I tried one of the conventional medications. Why LDN first? Because the overwhelming fatigue that can come with this illness is often exacerbated by the drugs and I don't think that LDN has that as a side effect. I wish that I could be more certain of the good that LDN does, but because I have never taken it without another medication, I have no way of knowing the extent to which it works. I do know that in the past year my whole body has become weaker, but I am getting older and I am pretty sedentary. So why do I feel so strongly about LDN? I honestly don't know. What I do know is that, for me, it might just be a security blanket in a little pill, but I don't want to be without it.
Taking this medicine has been an incredible relief after my experiences (horrible reactions and pain) from Avonex. I researched this medication online myself, took the info to Dr. Mary Ann Miknevich, who was very familiar with LDN, and thus I became a client of MAA. I have had nothing but positive experience taking this off-label drug, and, more importantly, no relapses! Between LDN and my daily course of exercise, physical rehab when needed (I'm also hyper-mobile and get out of proper back alignment easily), and one treatment of Stem Cell Therapy (both allogeneic mesenchymal and autologous adipose stem cells) in Panama City, I'm doing far better than I had hoped after my diagnosis. Keep up the good work - I need you!
